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Table 1 Abnormal health findings considered as the exclusion criteria

From: Oxygen uptake efficiency plateau is unaffected by fitness level - the NOODLE study

1. Pulmonary diseases

- Chronic obstructive pulmonary disease

- poorly controlled bronchial asthma

- blood saturation < 95%

2. Cardiovascular diseases

- significant heart rhythm disturbances in the 12-lead ECG (e.g., ventricular and supraventricular arrhythmias, atrial fibrillation)

- features of myocardial ischemia,

- prolongation of the QT interval in the 12-lead ECG

- structural heart disorders detected in cardiac echocardiography (e.g., hemodynamically relevant valvular defects, hypertrophic cardiomyopathy, systolic dysfunction of the right or left ventricle),

- decompensated blood pressure (with increases above 160/100 mmHg).

3. Neurological and mental disorders

4. Significant deviations found in CBC

- Leukocytosis above 10 000 ∙ mm− 3

- Anaemia with Hb level < 10 g ∙ d− 1

5. Exercise-limiting musculoskeletal injuries

  1. Note Any of the above health conditions were considered as the mandatory exclusion criteria during pre-participation medical follow-up. Abbreviations: 12-lead ECG, 12-lead electrocardiography; CBC, complete blood count; Hb, blood haemoglobin concentration