Effects of multicomponent exercise intervention on cardiometabolic risk factors in children and young adults with cerebral palsy: a multiple-baseline trial

Savikangas, Tiina; Valadão, Pedro; Haapala, Eero A.; Finni, Taija

doi:10.1186/s13102-024-01006-0

BMC Sports Science, Medicine and Rehabilitation

Table 3 The impact of the three-month EXECP intervention on cardiometabolic risk factors in children and young adults with cerebral palsy. Results from the linear mixed-effects models

From: Effects of multicomponent exercise intervention on cardiometabolic risk factors in children and young adults with cerebral palsy: a multiple-baseline trial

			95% Confidence interval
Outcome	Effect	β	Lower	Upper	P
Weight ^a	Intercept	50.21	43.41	57.02	< 0.001
	Time: Pre2 - Post	-0.97	-2.49	0.55	0.216
	Time: Pre1 - Post	-2.84	-4.36	-1.32	< 0.001
	Sex: Female - Male	12.29	-0.88	25.47	0.088
	Age	8.77	2.84	14.70	0.006
	Age^2	-0.22	-0.40	-0.04	0.024
Body fat percentage ^a	Intercept	19.13	14.07	24.19	< 0.001
Body fat percentage ^a	Time: Pre2 - Post	-1.03	-2.60	0.53	0.202
	Time: Pre1 - Post	-2.26	-3.82	-0.69	0.007
	Sex: Female - Male	15.88	6.08	25.69	0.007
	Age	0.02	-5.72	5.77	0.993
	Age^2	-0.02	-0.20	0.16	0.850
Skeletal muscle mass index ^a	Intercept	8.36	7.86	8.87	< 0.001
Skeletal muscle mass index ^a	Time: Pre2 - Post	-0.06	-0.21	0.09	0.447
	Time: Pre1 - Post	-0.19	-0.35	-0.04	0.017
	Sex: Female - Male	-0.17	-1.14	0.80	0.742
	Age	0.70	0.13	1.26	0.020
	Age^2	-0.02	-0.04	-0.00	0.054
Systolic blood pressure	Intercept	114.58	110.15	119.02	< 0.001
	Time: Pre2 - Post	-0.71	-3.85	2.43	0.660
	Time: Pre1 - Post	0.51	-2.63	3.65	0.752
	Sex: Female - Male	-2.86	-10.96	5.24	0.500
	Age	8.08	1.80	14.37	0.021
	Age^2	-0.23	-0.43	-0.04	0.032
Diastolic blood pressure	Intercept	60.40	57.67	63.13	< 0.001
	Time: Pre2 - Post	-1.75	-4.94	1.45	0.292
	Time: Pre1 - Post	0.56	-2.63	3.75	0.733
	Sex: Female - Male	4.61	0.67	8.55	0.038
	Age	2.29	-0.92	5.50	0.183
	Age^2	-0.07	-0.17	0.03	0.179
Pulse wave velocity	Intercept	5.83	5.56	6.11	< 0.001
	Time: Pre2 - Post	-0.15	-0.46	0.17	0.372
	Time: Pre1 - Post	0.30	-0.02	0.61	0.073
	Sex: Female - Male	0.74	0.35	1.14	0.003
	Age	0.37	0.05	0.70	0.039
	Age^2	-0.01	-0.02	-0.00	0.034
HDL cholesterol ^a	Interceot	1.63	1.47	1.79	< 0.001
	Time: Pre2 - Post	-0.02	-0.16	0.12	0.815
	Time: Pre1 - Post	-0.11	-0.25	0.03	0.137
	Sex: Female - Male	0.04	-0.24	0.32	0.803
	Age	-0.27	-0.49	-0.05	0.031
	Age^2	0.01	0.00	0.02	0.028
LDL cholesterol ^ab	Intercept	2.29	1.88	2.69	< 0.001
	Time: Pre2 - Post	-0.12	-0.30	0.07	0.231
	Time: Pre1 - Post	-0.17	-0.36	0.02	0.083
	Sex: Female - Male	0.01	-0.82	0.84	0.984
	Age	-0.16	-0.76	0.43	0.598
	Age^2	0.00	-0.02	0.02	0.680
Triglycerides ^ab	Intercept	0.83	0.68	0.98	< 0.001
	Time: Pre2 - Post	-0.05	-0.22	0.12	0.544
	Time: Pre1 - Post	-0.06	-0.23	0.11	0.495
	Sex: Female - Male	0.17	-0.06	0.39	0.168
	Age	-0.01	-0.19	0.17	0.911
	Age^2	0.00	-0.00	0.01	0.786
Glucose ^a	Intercept	5.29	5.01	5.56	< 0.001
	Time: Pre2 - Post	0.10	-0.10	0.29	0.338
	Time: Pre1 - Post	-0.08	-0.27	0.11	0.429
	Sex: Female - Male	-0.19	-0.68	0.30	0.463
	Age	0.21	-0.17	0.60	0.287
	Age^2	-0.01	-0.02	0.00	0.211
Cardiometabolic risk score ^c	Intercept	0.97	-1.39	3.34	0.431
	Time: Pre2 - Post	-0.71	-2.57	1.15	0.462
	Time: Pre1 - Post	-0.56	-2.38	1.27	0.555
	Sex: Female - Male	0.22	-3.89	4.34	0.917
	Age	1.69	-1.65	5.03	0.338
	Age^2	-0.05	-0.16	0.05	0.320

Note Abbreviations EXECP EXErcise for Cerebral Palsy; β unstandardized parameter estimates; Pre1 the first baseline measurement; Pre2 the second baseline measurement; Post post-intervention measurement; HDL high-density lipoprotein; LDL low-density lipoprotein
^aOne participant was excluded due to missing data in all measurements
^bOne participant was excluded as an extreme outlier based on a visual inspection of the residual Q-Q plot and histogram
^cTwo participants were excluded due to missing data in both measurements

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ISSN: 2052-1847

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